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  • ExperimentSetReplicate13
    • Dataset
  • Synthetic condensation assay of tudor domain13
    • Sample
    Treatments
    Assay Details
    Set Type
  • Replicate13
    • UUID
    16 Common Properties
     Project
    4DN
     Lab
    Karla Neugebauer, YALE
     Experiment Category
    Microscopy
     Experiment Type
    OptoDroplet
     Organism
    Mouse
     Sample Type
    immortalized cells
     Sample Tier
    Unclassified
     Sample Category
    Other
     Organ/System
    No value
     Tissue Source
    embryonic fibroblast
     Publication
    Courchaine EM et al. (2021) PMID:34115980
     Modifications
    No value
     Center
    TCPA - Neugebauer
     Status
    Released
     Commendations
    No value
     Warnings
    Biosample Metadata Incomplete
    Title
    Experiment Type
    Biosample
    Dataset
    Condition
    Assay Details
    Lab
    4DNESGSHWGUK
    OptoDroplet
    NIH-3T3 expressing SMN tudor (Y130D) Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain (Y130D mutant)
    Target
    SMN1 engineered reagent protein with Y130D Amino acid substitution, C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESRORWX8M
    OptoDroplet
    NIH-3T3 expressing SMN tudor (Y109L) Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain (Y109L mutant)
    Target
    SMN1 engineered reagent protein with Y109L Amino acid substitution, C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESGOUKUHY
    OptoDroplet
    NIH-3T3 expressing SMN tudor (W102L) Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain (W102L mutant)
    Target
    SMN1 engineered reagent protein with W102L Amino acid substitution, C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESQJS4P53
    OptoDroplet
    NIH-3T3 expressing SMN tudor (E134K) Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain (E134K mutant)
    Target
    SMN1 engineered reagent protein with E134K Amino acid substitution, C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESLBSY7UC
    OptoDroplet
    NIH-3T3 expressing SMN tudor (F118L) Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain (F118L mutant)
    Target
    SMN1 engineered reagent protein with F118L Amino acid substitution, C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESZZ8T7O9
    OptoDroplet
    NIH-3T3 expressing SMNDC1 tudor Cry2
    Synthetic condensation assay of tudor domain
    Spf30 tudor domain
    Target
    SMNDC1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESMFGLQ3U
    OptoDroplet
    NIH-3T3 expressing SMN tudor Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain, EPZ015666 treated
    Target
    SMN1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESM8F8PP5
    OptoDroplet
    NIH-3T3 expressing SMN tudor Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain, MS023 + EPZ015666 treated
    Target
    SMN1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESI1DYYLS
    OptoDroplet
    NIH-3T3 expressing SMN tudor Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain, MS023 treated
    Target
    SMN1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESPZNHYSY
    OptoDroplet
    NIH-3T3 expressing SMN tudor Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain, mock treated
    Target
    SMN1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNES9JHBEZC
    OptoDroplet
    NIH-3T3 expressing SMN tudor Cry2
    Synthetic condensation assay of tudor domain
    SMN tudor domain
    Target
    SMN1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNESVT8QSLU
    OptoDroplet
    NIH-3T3 expressing Cry2 (negative control)
    Synthetic condensation assay of tudor domain
    mCherry-Cry2 negative control
    Target
    engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    4DNES49WH1QD
    OptoDroplet
    NIH-3T3 expressing hnRNPA1 IDR Cry2
    Synthetic condensation assay of tudor domain
    HNRNPA1 IDR
    Target
    HNRNPA1 engineered reagent protein with C-terminus mCherry, Cry2
    Karla Neugebauer, YALE
    - fin -