Included Properties
Data Type
Experiment Type
Sample
Treatments
Assay Details
Status
16 Common Properties
Project
4DN
Lab
Karla Neugebauer, YALE
Experiment Category
Microscopy
Dataset
Synthetic condensation assay of tudor domain
Organism
Mouse
Sample Type
immortalized cells
Sample Tier
Unclassified
Sample Category
Other
Organ/System
No value
Tissue Source
embryonic fibroblast
Publication
Courchaine EM et al. (2021) PMID:34115980
Modifications
No value
Center
TCPA - Neugebauer
Set Type
Replicate
Commendations
No value
Warnings
Biosample Metadata Incomplete
13 Results
Title
Experiment Type
Biosample
Dataset
Condition
Assay Details
Lab
OptoDroplet
NIH-3T3 expressing SMN tudor (Y130D) Cry2
Synthetic condensation assay of tudor domain
SMN tudor domain (Y130D mutant)
Target
SMN1 engineered reagent protein with Y130D Amino acid substitution, C-terminus mCherry, Cry2
OptoDroplet
NIH-3T3 expressing SMN tudor (Y109L) Cry2
Synthetic condensation assay of tudor domain
SMN tudor domain (Y109L mutant)
Target
SMN1 engineered reagent protein with Y109L Amino acid substitution, C-terminus mCherry, Cry2
OptoDroplet
NIH-3T3 expressing SMN tudor (W102L) Cry2
Synthetic condensation assay of tudor domain
SMN tudor domain (W102L mutant)
Target
SMN1 engineered reagent protein with W102L Amino acid substitution, C-terminus mCherry, Cry2
OptoDroplet
NIH-3T3 expressing SMN tudor (E134K) Cry2
Synthetic condensation assay of tudor domain
SMN tudor domain (E134K mutant)
Target
SMN1 engineered reagent protein with E134K Amino acid substitution, C-terminus mCherry, Cry2
OptoDroplet
NIH-3T3 expressing SMN tudor (F118L) Cry2
Synthetic condensation assay of tudor domain
SMN tudor domain (F118L mutant)
Target
SMN1 engineered reagent protein with F118L Amino acid substitution, C-terminus mCherry, Cry2
OptoDroplet
NIH-3T3 expressing SMNDC1 tudor Cry2
Synthetic condensation assay of tudor domain
Spf30 tudor domain
Target
SMNDC1 engineered reagent protein with C-terminus mCherry, Cry2
OptoDroplet
NIH-3T3 expressing SMN tudor Cry2
Synthetic condensation assay of tudor domain
SMN tudor domain, EPZ015666 treated
Target
SMN1 engineered reagent protein with C-terminus mCherry, Cry2
OptoDroplet
NIH-3T3 expressing SMN tudor Cry2
Synthetic condensation assay of tudor domain
SMN tudor domain, MS023 + EPZ015666 treated
Target
SMN1 engineered reagent protein with C-terminus mCherry, Cry2
OptoDroplet
NIH-3T3 expressing SMN tudor Cry2
Synthetic condensation assay of tudor domain
SMN tudor domain, MS023 treated
Target
SMN1 engineered reagent protein with C-terminus mCherry, Cry2
OptoDroplet
NIH-3T3 expressing SMN tudor Cry2
Synthetic condensation assay of tudor domain
SMN tudor domain, mock treated
Target
SMN1 engineered reagent protein with C-terminus mCherry, Cry2
OptoDroplet
NIH-3T3 expressing SMN tudor Cry2
Synthetic condensation assay of tudor domain
SMN tudor domain
Target
SMN1 engineered reagent protein with C-terminus mCherry, Cry2
OptoDroplet
NIH-3T3 expressing Cry2 (negative control)
Synthetic condensation assay of tudor domain
mCherry-Cry2 negative control
Target
engineered reagent protein with C-terminus mCherry, Cry2
OptoDroplet
NIH-3T3 expressing hnRNPA1 IDR Cry2
Synthetic condensation assay of tudor domain
HNRNPA1 IDR
Target
HNRNPA1 engineered reagent protein with C-terminus mCherry, Cry2
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